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| A DLM/FD/IB Method for Simulating Compound Cell Interacting with Red Blood Cells in a Microchannel |
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Citation： |
Shihai ZHAO,Yao YU,Tsorng-Whay PAN,Roland GLOWINSKI.A DLM/FD/IB Method for Simulating Compound Cell Interacting with Red Blood Cells in a Microchannel[J].Chinese Annals of Mathematics B,2018,39(3):535~552 |
| Page view： 1182
Net amount： 1384 |
Authors： |
Shihai ZHAO; Yao YU;Tsorng-Whay PAN;Roland GLOWINSKI |
Foundation： |
This work was supported by the National Science
Foundation of the United States (Nos.DMS-0914788, DMS-1418308). |
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| Abstract： |
In this article, a computational model and related methodologies
have been tested for simulating the motion of a malaria infected red
blood cell (iRBC for short) in Poiseuille flow at low Reynolds
numbers. Besides the deformability of the red blood cell membrane,
the migration of a neutrally buoyant particle (used to model the
malaria parasite inside the membrane) is another factor to determine
the iRBC motion. Typically an iRBC oscillates in a Poiseuille flow
due to the competition between these two factors. The interaction of
an iRBC and several RBCs in a narrow channel shows that, at lower
flow speed, the iRBC can be easily pushed toward the wall and stay
there to block the channel. But, at higher flow speed, RBCs and iRBC
stay in the central region of the channel since their migrations are
dominated by the motion of the RBC membrane. |
Keywords： |
Compound cell, Red blood cells, Elastic spring model, Fictitiousdomain method, Immersed boundary method, Microchannel |
Classification： |
76Z05, 76M10 |
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